These findings are relevant to the diagnosis and therapy of allergic and autoimmune diseases, as well as cancers and transplantation.ĭr. This work uncovered a previously unrecognized role of: B-1a B cells, NKT cells, IL-4, complement, serotonin and mast cells. Askenase discovered the series of steps from challenge with antigen in a sensitized host to the entry of T cells into the site of challenge. Working with the well-known models of cutaneous immune hypersensitivity and immunity, Dr. Hsu also collaborates with researchers around the country on other observational clinical studies in hereditary angioedema. She has published on the safety and efficacy of several rapid drug desensitization protocols and helps to identify patients for clinical studies within our section. Hsu has participated over the years in a variety of clinical trials for pharmacotherapeutics in hereditary angioedema and chronic rhinosinusitis. Most recently he started the Yale Allergy & Immunology Contact Dermatitis Program, where he serves as Program Director, and conducts clinical research into allergic skin diseases.ĭr. Prior to entering full time academic practice, he conducted post-doctoral research focusing on small peptide therapeutics for auto-immune diseases, as well as work elucidating the mechanisms behind anti-IgE therapy in chronic urticaria. ![]() Steele cares for patients in the full range of allergic and immunologic diseases. Shin’s overall research goal is understanding how immune alterations occur and affect the pathogenesis of such disorders in relation to their genetic defects, clinical presentations and comorbidities.ĭr. Her research focuses on characterizing clinical phenotypes of patients with primary immune deficiencies and immune dysregulation using in-depth immune profiling techniques. ![]() She developed the clinical immunology-oncology program and is establishing databases and biorepositories of patients on immune modulators with the collaborative effort between the internal medicine subspecialists who are treating immune related adverse events from immune modulators.ĭr. Price's research goals are to understand the relationship between autoimmunity, immune deficiency and tumor immunology. Liu’s research focuses on understanding the production and role of gut immunoglobulin A in food allergy.ĭr. ![]() Kwah also has an interest in understanding the relationship between upper and lower airways diseases, such as chronic sinusitis, allergic rhinitis, asthma, and bronchiectasis.ĭr. Their research interest is in understanding the consequence of penicillin allergy in pregnancy and ways to enhance patient care to improve maternal and neonatal outcomes. ![]() Moeun Son in Maternal Fetal Medicine in caring for obstetric patients with allergic and immunologic diseases. Identification of these particular pathways have the potential for furthering our understanding of immunodeficiency, and possible future targeted therapies.ĭr. Kuster’s research interests include leveraging genetic testing in immunodeficiency to help identify specific disease associated variants. Kang’s lab has defined subsets of T cells with distinct cellular characteristics based on the expression of cytokine receptors on T cells in health and disease as well as the interactions of such cell subsets with monocytes and other immune cells.ĭr. Kang’s laboratory is to understand the human immune system in health and disease including autoimmunity, inflammation, primary immunodeficiency and atopic diseases using biological samples and clinical data. She is particularly interested in designing interventions to promote the application of evidence-based practices and guidelines for patients with antibiotic allergy labels, particularly in vulnerable patient populations. Belmont's research interests include drug allergy and the intersection between drug allergy (e.g., antibiotic allergy labels) and antibiotic stewardship.
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